LOXL1 polyclonal, anti-human
€469.00
In stock
SKU
252215
Catalog Nr.: 252215
Size: 0.1 mg
Isotype: Rabbit Ig
Applications: E, WB, IHC
Datasheet
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Size: 0.1 mg
Isotype: Rabbit Ig
Applications: E, WB, IHC
Datasheet
Request Information
Protein Family: Enzymes
Pathway and Disease: Signaling Molecules and Interaction
Description:
Lysyl oxidase homolog 1 (LOXL1) is an enzyme which is active on elastin and collagen. LOXL1 is expressed in ocular tissue including the iris, ciliary body, lens, and optic nerve. LOXL1 is not expressed in the retina. Genetic variations in LOXL1 are a cause of susceptibility to exfoliation syndrome (XFS), also called exfoliation glaucoma (XFG). XFS is a disorder characterized by the accumulation of abnormal fibrillar deposits in the anterior segment of the eye.
Alternate Names: Lysyl oxidase homolog 1, Lysyl oxidase-like protein 1, LOL, LOXL1, LOXL
Application Notes: E: 1:1,000-1:10,000; WB: 1:500-1:1,000; IHC: 1:50-1:500
Accession No.: Q08397
Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human LOXL1.
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by immunogen-affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Product Citations:
[1] Alsofi L. et al. 2015. Department of Molecular and Cell Biology, Henry M. Goldman School of Dental Medicine, Boston University. Feb
98(2):172-85. PMID: 26538021.
Pathway and Disease: Signaling Molecules and Interaction
Description:
Lysyl oxidase homolog 1 (LOXL1) is an enzyme which is active on elastin and collagen. LOXL1 is expressed in ocular tissue including the iris, ciliary body, lens, and optic nerve. LOXL1 is not expressed in the retina. Genetic variations in LOXL1 are a cause of susceptibility to exfoliation syndrome (XFS), also called exfoliation glaucoma (XFG). XFS is a disorder characterized by the accumulation of abnormal fibrillar deposits in the anterior segment of the eye.
Alternate Names: Lysyl oxidase homolog 1, Lysyl oxidase-like protein 1, LOL, LOXL1, LOXL
Application Notes: E: 1:1,000-1:10,000; WB: 1:500-1:1,000; IHC: 1:50-1:500
Accession No.: Q08397
Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human LOXL1.
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by immunogen-affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Product Citations:
[1] Alsofi L. et al. 2015. Department of Molecular and Cell Biology, Henry M. Goldman School of Dental Medicine, Boston University. Feb
98(2):172-85. PMID: 26538021.
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