LOXL1 polyclonal, anti-human

Protein Family: Enzymes

Pathway and Disease: Signaling Molecules and Interaction

Description:
Lysyl oxidase homolog 1 (LOXL1) is active on elastin and collagen substrates. LOXL1 is expressed in ocular tissues including the iris, ciliary body, lens and optic nerve. LOXL1 is not detected in the retina. Genetic variations in LOXL1 are a cause of susceptibility to exfoliation syndrome (XFS), also called exfoliation glaucoma (XFG). XFS is a disorder characterized by accumulation of abnormal fibrillar deposits in the anterior segment of the eye.

Alternate Names: Lysyl oxidase homolog 1, Lysyl oxidase-like protein 1, LOL, LOXL1, LOXL

Application Notes: E: 1:10,000-1:50,000; WB: 1:100-1:1,000; IHC: 1:50-1:250

Accession No.: Q08397

Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the center region of human LOXL1.

Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 0.5% BSA with 0.09% sodium azide. Antibody was purified by immunogen affinity chromatography.

Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.