LOXL1 polyclonal, anti-human, mouse, rat
€388.00
In stock
SKU
BS70481
Background:
This gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family. [provided by RefSeq, Jul 2008]
Alternative Name:
Lysyl oxidase homolog 1, Lysyl oxidase-like protein 1, LOL, LOXL1, LOXL
Application Dilution: WB: 1:1000 - 1:3000
Specificity: LOXL1 polyclonal antibody detects endogenous levels of LOXL1 protein.
Immunogen:
Recombinant protein of human LOXL1.
MW: ~ 63 kDa
Swis Prot.: Q08397
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
This gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family. [provided by RefSeq, Jul 2008]
Alternative Name:
Lysyl oxidase homolog 1, Lysyl oxidase-like protein 1, LOL, LOXL1, LOXL
Application Dilution: WB: 1:1000 - 1:3000
Specificity: LOXL1 polyclonal antibody detects endogenous levels of LOXL1 protein.
Immunogen:
Recombinant protein of human LOXL1.
MW: ~ 63 kDa
Swis Prot.: Q08397
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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