LOXL2 antibody (clone 5D2), anti-human
€435.00
In stock
SKU
AC-AT2735a
Catalog Number: AC-AT2735a
Size: 100 µg
Isotype: mouse IgG2b Kappa
Applications: WB, E
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Size: 100 µg
Isotype: mouse IgG2b Kappa
Applications: WB, E
Request Information AC-AT2735a">Request Information
Background:
This gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family.
Other Names:
Lysyl oxidase homolog 2, Lysyl oxidase-like protein 2, Lysyl oxidase-related protein 2, Lysyl oxidase-related protein WS9-14, LOXL2
Antigen Type:
Recombinant Protein
Gene Name: LOXL2
Gene ID: 4017
NCBI Accession: NP_002309.1
Primary Accession: Q9Y4K0
Other Accession: NM_002318
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
This gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family.
Other Names:
Lysyl oxidase homolog 2, Lysyl oxidase-like protein 2, Lysyl oxidase-related protein 2, Lysyl oxidase-related protein WS9-14, LOXL2
Antigen Type:
Recombinant Protein
Gene Name: LOXL2
Gene ID: 4017
NCBI Accession: NP_002309.1
Primary Accession: Q9Y4K0
Other Accession: NM_002318
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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