LRAT Polyclonal Antibody

Background:
The protein encoded by this gene localizes to the endoplasmic reticulum, where it catalyzes the esterification of all-trans-retinol into all-trans-retinyl ester. This reaction is an important step in vitamin A metabolism in the visual system. Mutations in this gene have been associated with early-onset severe retinal dystrophy and Leber congenital amaurosis 14. Alternative splicing results in multiple transcript variants.

Research Area: Cancer, Metabolism, Neuroscience, Signal Transduction

Synonyms:
LCA14, Lecithin retinol acyltransferase (phosphatidylcholine retinol O acyltransferase), Lecithin retinol acyltransferase, LRAT, LRAT, Phosphatidylcholine retinol O acyltransferase, Phosphatidylcholine--retinol O-acyltransferase

Immunogen: Fusion protein of human LRAT

Swissprot: O95237
Gene Accession: BC031053

Calculated MW: 26 kDa
Observed MW: Refer to figures

Purification Method: Antigen affinity purification

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Concentration: 0.96 mg/mL
Dilution: WB 1:500-1:2000, IHC 1:50-1:200, ELISA 1:5000-1:10000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.