LRAT Polyclonal Antibody

Background:
The protein encoded by this gene localizes to the endoplasmic reticulum, where it catalyzes the esterification of all-trans-retinol into all-trans-retinyl ester. This reaction is an important step in vitamin A metabolism in the visual system. Mutations in this gene have been associated with early-onset severe retinal dystrophy and Leber congenital amaurosis 14. Alternative splicing results in multiple transcript variants.

Research Area: Cancer, Metabolism, Neuroscience, Signal Transduction

Synonyms:
LRAT, LCA14

Immunogen: Recombinant fusion protein of human LRAT (NP_004735.2).

Swissprot: O95237
Gene ID: 9227

Calculated MW: 25 kDa
Observed MW: 24 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "WB 1:500-1:2000 IF 1:50-1:100"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.