LRIG1 Polyclonal Antibody

Background:
Leucine-rich repeats and immunoglobulin-like domains protein 1is aproteinthat in humans is encoded by theLRIG1gene.It encodes atransmembrane proteinthat has been shown to interact with receptor tyrosine kinases of theEGFR-family,METandRET. Acts as a feedback negative regulator of signaling by receptor tyrosine kinases, through a mechanism that involves enhancement of receptor ubiquitination and accelerated intracellular degradation.

Research Area: Cancer

Synonyms:
Leucine rich repeat protein, Leucine rich repeat protein LRIG1, leucine rich repeats and immunoglobulin like domains 1, Leucine-rich repeats and immunoglobulin-like domains protein 1, leucine-rich repeats- and immunoglobulin-like domains-cotnaining protein 1, LIG 1, LIG-1, LIG1, Lrig1, LRIG1, Ortholog of mouse integral membrane glycoprotein LIG 1

Immunogen: Synthetic peptide of human LRIG1

Swissprot: Q96JA1
Gene Accession: NP_056356

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 1 mg/mL
Dilution: IHC 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-50076