LRIG1 Polyclonal Antibody

Background:
Leucine-rich repeats and immunoglobulin-like domains protein 1is aproteinthat in humans is encoded by theLRIG1gene.It encodes atransmembrane proteinthat has been shown to interact with receptor tyrosine kinases of theEGFR-family, METandRET. Acts as a feedback negative regulator of signaling by receptor tyrosine kinases, through a mechanism that involves enhancement of receptor ubiquitination and accelerated intracellular degradation.

Research Area: Cancer

Synonyms:
LRIG1, LIG-1, LIG1

Immunogen: Recombinant fusion protein of human LRIG1 (NP_056356.2).

Swissprot: Q96JA1
Gene ID: 26018

Calculated MW: 116 kDa/119 kDa
Observed MW: 160 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "WB 1:1000-1:2000"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.