LRP-5/6 polyclonal, anti-human, mouse, rat antibody
€275.00
In stock
SKU
AC-ABV10546-100
Catalog Number: AC-ABV10546-100
Size: 100 µg
Host: Rabbit IgG
Applications: WB
Datasheet
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Size: 100 µg
Host: Rabbit IgG
Applications: WB
Datasheet
Request Information
Background:
LDL-related proteins LRP-5 and LRP-6. are members of the LDL receptor superfamily, which were found to be involved in the canonical Wnt signaling pathway. Mammalian LRP-6 was shown to bind to Wnt-1 and enhance Induced-induced developmental processes in Xenopus embryos. Mice lacking LRP-6 exhibited developmental defects that are similar to those caused by deficiencies in various Want proteins. Recent work also shows that Want proteins induce the binding of LRP-5 to Axin, leading Axin degradation and β-catenin stabilization.
Other Names:
LRP-5 , LRP -6
Primary Accession: O75197
Gene Name: LRP5 {ECO:0000303|PubMed:24706814, ECO:0000312|HGNC:HGNC:6697}
Gene ID: 4041
Concentration (mg/ml): 0.5 mg/ml
LDL-related proteins LRP-5 and LRP-6. are members of the LDL receptor superfamily, which were found to be involved in the canonical Wnt signaling pathway. Mammalian LRP-6 was shown to bind to Wnt-1 and enhance Induced-induced developmental processes in Xenopus embryos. Mice lacking LRP-6 exhibited developmental defects that are similar to those caused by deficiencies in various Want proteins. Recent work also shows that Want proteins induce the binding of LRP-5 to Axin, leading Axin degradation and β-catenin stabilization.
Other Names:
LRP-5 , LRP -6
Primary Accession: O75197
Gene Name: LRP5 {ECO:0000303|PubMed:24706814, ECO:0000312|HGNC:HGNC:6697}
Gene ID: 4041
Concentration (mg/ml): 0.5 mg/ml
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