LRP5 polyclonal, anti-human

Background:
This gene encodes a transmembrane low-density lipoprotein receptor that binds and internalizes ligands in the process of receptor-mediated endocytosis. This protein also acts as a co-receptor with Frizzled protein family members for transducing signals by Wnt proteins and was originally cloned on the basis of its association with type 1 diabetes mellitus in humans. This protein plays a key role in skeletal homeostasis and many bone density related diseases are caused by mutations in this gene. Mutations in this gene also cause familial exudative vitreoretinopathy.

Other Names:
Low-density lipoprotein receptor-related protein 5, LRP-5, LRP5, LR3, LRP7

Antigen Types:
Synthetic Peptide

Gene Name:
LRP5 {ECO:0000303|PubMed:24706814, ECO:0000312|HGNC:HGNC:6697}
Gene ID:
4041
Primary Accession: O75197
Other Accession: NP_002326;4041;