LRP5 polyclonal (C-term), anti-mouse

LRP5 polyclonal (C-term), anti-mouse

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In stock
SKU
AC-AP14655b
Catalog Number: AC-AP14655b
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB32191
Applications: WB
Datasheet

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Background:
This gene encodes a transmembrane low-density lipoprotein receptor that binds and internalizes ligands in the process of receptor-mediated endocytosis. This protein also acts as a co-receptor with Frizzled protein family members for transducing signals by Wnt proteins and was originally cloned on the basis of its association with type 1 diabetes mellitus in humans. This protein plays a key role in skeletal homeostasis and many bone density related diseases are caused by mutations in this gene. Mutations in this gene also cause familial exudative vitreoretinopathy.

Other Names:
Low-density lipoprotein receptor-related protein 5, LRP-5, LRP5, LR3, LRP7

Target/Specificity:
This LRP5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1163-1190 amino acids from the C-terminal region of human LRP5.

Antigen Region:
1163-1190

Antigen Type: Synthetic Peptide

Gene Name: LRP5 {ECO:0000303|PubMed:24706814, ECO:0000312|HGNC:HGNC:6697}
Gene ID: 4041
Primary Accession: O75197
NCBI Accession: NP_002326.2
Other Accession: Q91VN0; NP_002326.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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