LRPAP (clone AT8G8), anti-human
€0.00
In stock
SKU
ATGA0321
Catalog NumberATGA0321
Isotype
Mouse IgG1 kappa
Applications:
ELISA, WB, ICC/IF
Datasheet
Questions? Contact us!
Isotype
Mouse IgG1 kappa
Applications:
ELISA, WB, ICC/IF
Datasheet
Questions? Contact us!
Description
Alpha-2-macroglobulin receptor-associated protein, also known as low density lipoprotein receptor-related protein-associated protein 1, RAP and LRPAP1, is a 39 kDa protein and a member of the alpha-2-MRAP family. LRPAP1 is a receptor antagonist that interacts with several members of the low density lipoprotein (LDL) receptor gene family. Upon binding to these receptors, LRPAP1 inhibits all ligand interactions with the receptors. LRPAP1 is present on cell surface forming a complex with the alpha-2-macroglobulin receptor heavy and light chains. LRPAP1 is present on the cell surface, where it is an effective inhibitor of ligand binding to the kidney glycoprotein 330 (gp330) yet it is most abundant in the endoplasmic reticulum lumen and may function in receptor folding and/or trafficking.Alternative Names
alpha-2-macroglobulin receptor-associated protein, A2MRAP, A2RAP, HBP44, MGC138272, MRAP, RAPConcentration
1mg/ml (determined by BCA assay)Concentration
Liquid in. Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% glycerolStorage: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Alpha-2-macroglobulin receptor-associated protein, also known as low density lipoprotein receptor-related protein-associated protein 1, RAP and LRPAP1, is a 39 kDa protein and a member of the alpha-2-MRAP family. LRPAP1 is a receptor antagonist that interacts with several members of the low density lipoprotein (LDL) receptor gene family. Upon binding to these receptors, LRPAP1 inhibits all ligand interactions with the receptors. LRPAP1 is present on cell surface forming a complex with the alpha-2-macroglobulin receptor heavy and light chains. LRPAP1 is present on the cell surface, where it is an effective inhibitor of ligand binding to the kidney glycoprotein 330 (gp330) yet it is most abundant in the endoplasmic reticulum lumen and may function in receptor folding and/or trafficking.Alternative Names
alpha-2-macroglobulin receptor-associated protein, A2MRAP, A2RAP, HBP44, MGC138272, MRAP, RAPConcentration
1mg/ml (determined by BCA assay)Concentration
Liquid in. Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% glycerolStorage: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
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