LRRC16A Polyclonal Antibody

Background:
Cell membrane-cytoskeleton-associated protein that plays a role in the regulation of actin polymerization at the barbed end of actin filaments. Prevents F-actin heterodimeric capping protein (CP) activity at the leading edges of migrating cells, and hence generates uncapped barbed ends and enhances actin polymerization, however, seems unable to nucleate filaments (PubMed:16054028). Plays a role in lamellipodial protrusion formations and cell migration (PubMed:19846667).

Research Area: Signal transduction

Synonyms:
Acan 125, Capping protein, Arp2/3, and myosin I linker, CARMIL homolog, leucine rich repeat containing 16, Leucine-rich repeat-containing protein 16A, LR16A, Lrrc16 protein, LRRC16A, p116

Immunogen: Synthetic peptide of human LRRC16A

Swissprot: Q5VZK9
Gene Accession: NP060110

Purification Method: Antigen affinity purification

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Concentration: 0.6 mg/mL
Dilution: IHC 1:30-1:150, ELISA 1:5000-1:10000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.