LRRFIP1 (clone ), anti-human, mouse
€388.00
In stock
SKU
MB0034
Background:
Transcriptional repressor which preferentially binds to the GC-rich consensus sequence (5'-AGCCCCCGGCG-3') and may regulate expression of TNF, EGFR and PDGFA. May control smooth muscle cells proliferation following artery injury through PDGFA repression. May also bind double-stranded RNA. Positively regulates Toll-like receptor (TLR) signaling in response to agonist probably by competing with the negative FLII regulator for MYD88-binding.
Alternative Name:
GC-binding factor 2, TAR RNA-interacting protein, GCF2, TRIP, FLAP1, GCF-2, FLAP-1, HUFI-1, FLIIAP1
Application Dilution: WB: 1:1000
Specificity: This antibody detects endogenous levels of LRRFIP1 and does not cross-react with related proteins
Immunogen:
Recombinant full length Human LRRFIP1.
MW: Predicted band size: 89KDa, Observed band size: 160KDa
Swis Prot.: Q32MZ4
Purification & Purity:
The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50%,glycerol
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
Transcriptional repressor which preferentially binds to the GC-rich consensus sequence (5'-AGCCCCCGGCG-3') and may regulate expression of TNF, EGFR and PDGFA. May control smooth muscle cells proliferation following artery injury through PDGFA repression. May also bind double-stranded RNA. Positively regulates Toll-like receptor (TLR) signaling in response to agonist probably by competing with the negative FLII regulator for MYD88-binding.
Alternative Name:
GC-binding factor 2, TAR RNA-interacting protein, GCF2, TRIP, FLAP1, GCF-2, FLAP-1, HUFI-1, FLIIAP1
Application Dilution: WB: 1:1000
Specificity: This antibody detects endogenous levels of LRRFIP1 and does not cross-react with related proteins
Immunogen:
Recombinant full length Human LRRFIP1.
MW: Predicted band size: 89KDa, Observed band size: 160KDa
Swis Prot.: Q32MZ4
Purification & Purity:
The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50%,glycerol
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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