LRRK2 (PARK8) Mutant G2019S Antibody Blocking Peptide
€363.00
In stock
SKU
AC-BP7100a
Background:
LRRK2 is a member of the leucine-rich repeat kinase family. The protein possesses an ankryin repeat region, a leucine-rich repeat (LRR) domain, a kinase domain, a DFG-like motif, a RAS domain, a GTPase domain, a MLK-like domain, and a WD40 domain. The protein is present largely in the cytoplasm but also associates with the mitochondrial outer membrane. Mutations in thisgene have been associated with Parkinson disease-8.
Other Names:
Leucine-rich repeat serine/threonine-protein kinase 2, Dardarin, LRRK2, PARK8
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP7100a was selected from the PARK8 region of human LRRK2 (PARK8) Mutant G2019S. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: LRRK2
Gene ID: 120892
Primary Accession: Q5S007
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
LRRK2 is a member of the leucine-rich repeat kinase family. The protein possesses an ankryin repeat region, a leucine-rich repeat (LRR) domain, a kinase domain, a DFG-like motif, a RAS domain, a GTPase domain, a MLK-like domain, and a WD40 domain. The protein is present largely in the cytoplasm but also associates with the mitochondrial outer membrane. Mutations in thisgene have been associated with Parkinson disease-8.
Other Names:
Leucine-rich repeat serine/threonine-protein kinase 2, Dardarin, LRRK2, PARK8
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP7100a was selected from the PARK8 region of human LRRK2 (PARK8) Mutant G2019S. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: LRRK2
Gene ID: 120892
Primary Accession: Q5S007
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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