LRRK2 Polyclonal Antibody

Background:
This gene is a member of the leucine-rich repeat kinase family and encodes a protein with an ankryin repeat region, a leucine-rich repeat (LRR) domain, a kinase domain, a DFG-like motif, a RAS domain, a GTPase domain, a MLK-like domain, and a WD40 domain. The protein is present largely in the cytoplasm but also associates with the mitochondrial outer membrane. Mutations in this gene have been associated with Parkinson disease-8.

Research Area: Cancer, Neuroscience

Synonyms:
LRRK2, AURA17, DARDARIN, PARK8, RIPK7, ROCO2

Immunogen: Recombinant fusion protein of human LRRK2 (NP_940980.3).

Swissprot: Q5S007
Gene ID: 120892

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: IHC 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.