LSM4 polyclonal, anti-human, mouse, rat
€388.00
In stock
SKU
BS8083
Background:
Sm and Sm-like (LSm) proteins form donut shaped heptameric complexes that are involved in various steps of RNA metabolism. Lsm proteins facilitate RNA protein interactions and structural changes that are required during ribosomal subunit assembly. LSm4, also called U6 snRNA-associated Sm-like protein or Glycine-rich protein (GRP), binds specifically to the 3'-terminal U-tract of U6 snRNA. Human LSm4 localizes to the cytoplasm in small, discrete foci. These foci are also the localization site for the mRNA decapping enzyme Dcp1/2 and the exonuclease, Xm1.
Alternative Name:
U6 snRNA-associated Sm-like protein LSm4, Glycine-rich protein, GRP, LSM4
Application Dilution: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200, IP: 1:50 - 1:100
Specificity: LSM4 polyclonal antibody detects endogenous levels of LSM4 protein.
Immunogen:
Recombinant full length Human LSM4.
MW: ~ 15 kDa
Swis Prot.: Q9Y4Z0
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
Sm and Sm-like (LSm) proteins form donut shaped heptameric complexes that are involved in various steps of RNA metabolism. Lsm proteins facilitate RNA protein interactions and structural changes that are required during ribosomal subunit assembly. LSm4, also called U6 snRNA-associated Sm-like protein or Glycine-rich protein (GRP), binds specifically to the 3'-terminal U-tract of U6 snRNA. Human LSm4 localizes to the cytoplasm in small, discrete foci. These foci are also the localization site for the mRNA decapping enzyme Dcp1/2 and the exonuclease, Xm1.
Alternative Name:
U6 snRNA-associated Sm-like protein LSm4, Glycine-rich protein, GRP, LSM4
Application Dilution: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200, IP: 1:50 - 1:100
Specificity: LSM4 polyclonal antibody detects endogenous levels of LSM4 protein.
Immunogen:
Recombinant full length Human LSM4.
MW: ~ 15 kDa
Swis Prot.: Q9Y4Z0
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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