LSP1 rabbit polyclonal, anti-human, mouse, rat

Backgroud: This gene encodes an intracellular F-actin binding protein. The protein is expressed in lymphocytes, neutrophils, macrophages, and endothelium and may regulate neutrophil motility, adhesion to fibrinogen matrix proteins, and transendothelial migration. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008],function:May play a role in mediating neutrophil activation and chemotaxis.,PTM:Phosphorylated by casein kinase II, protein kinase C and MAPKAPK2. Phosphorylation by PKC induces translocation from membrane to cytoplasm. Phosphorylation by MAPKAPK2 may regulate neutrophil chemotaxis.,subunit:Binds actin.,tissue specificity:Activated T-lymphocytes.,

Synonyms: LSP1, WP34, Lymphocyte-specific protein 1, 47 kDa actin-binding protein, 52 kDa phosphoprotein, pp52, Lymphocyte-specific antigen WP34

Gene Name: LSP1

Gene ID: 4046

SwissProt ID: P33241

Purification: Affinity purification

Storage: Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.