LTB monoclonal (C-term), anti-human
€0.00
In stock
SKU
AC-AM2016b
Catalog Number: AC-AM2016b
Size: 80 µl, 400 µl
Isotype: mouse IgM
Clone Name: 399CT9.3.4
Applications: WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: mouse IgM
Clone Name: 399CT9.3.4
Applications: WB
Datasheet
Request Information
Background:
Lymphotoxin beta is a type II membrane protein of the TNF family. It anchors lymphotoxin-alpha to the cell surface through heterotrimer formation. The predominant form on the lymphocyte surface is the lymphotoxin-alpha 1/beta 2 complex (e.g. 1 molecule alpha/2 molecules beta) and this complex is the primary ligand for the lymphotoxin-beta receptor. The minor complex is lymphotoxin-alpha 2/beta 1. LTB is an inducer of the inflammatory response system and involved in normal development of lymphoid tissue. Lymphotoxin-beta isoform b is unable to complex with lymphotoxin-alpha suggesting a function for lymphotoxin-beta which is independent of lympyhotoxin-alpha. Alternative splicing results in multiple transcript variants encoding different isoforms.
Other Names:
Lymphotoxin-beta, LT-beta, Tumor necrosis factor C, TNF-C, Tumor necrosis factor ligand superfamily member 3, LTB, TNFC, TNFSF3
Target/Specificity:
This LTB antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 199-227 amino acids from the C-terminal region of human LTB.
Antigen Region:
199-227
Antigen Type: Synthetic Peptide
Gene Name: LTB
Gene ID: 4050
Primary Accession: Q06643
NCBI Accession: NP_002332.1;NP_033666.1
Other Accession: Q9TSV8; NP_002332.1; NP_033666.1
Format: Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Euglobin precipitation followed by dialysis against PBS.
Lymphotoxin beta is a type II membrane protein of the TNF family. It anchors lymphotoxin-alpha to the cell surface through heterotrimer formation. The predominant form on the lymphocyte surface is the lymphotoxin-alpha 1/beta 2 complex (e.g. 1 molecule alpha/2 molecules beta) and this complex is the primary ligand for the lymphotoxin-beta receptor. The minor complex is lymphotoxin-alpha 2/beta 1. LTB is an inducer of the inflammatory response system and involved in normal development of lymphoid tissue. Lymphotoxin-beta isoform b is unable to complex with lymphotoxin-alpha suggesting a function for lymphotoxin-beta which is independent of lympyhotoxin-alpha. Alternative splicing results in multiple transcript variants encoding different isoforms.
Other Names:
Lymphotoxin-beta, LT-beta, Tumor necrosis factor C, TNF-C, Tumor necrosis factor ligand superfamily member 3, LTB, TNFC, TNFSF3
Target/Specificity:
This LTB antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 199-227 amino acids from the C-terminal region of human LTB.
Antigen Region:
199-227
Antigen Type: Synthetic Peptide
Gene Name: LTB
Gene ID: 4050
Primary Accession: Q06643
NCBI Accession: NP_002332.1;NP_033666.1
Other Accession: Q9TSV8; NP_002332.1; NP_033666.1
Format: Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Euglobin precipitation followed by dialysis against PBS.
| Is Featured? | No |
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