Lumican polyclonal, anti-human, mouse, rat

Background:
Lumican, a member of the small leucine-rich proteoglycans (SLRPs) family of proteins, is a keratan sulfate proteoglycan present in large quantities in the corneal stroma and in interstitial collagenous matrices of the heart, aorta, skeletal muscle, skin, and intervertebral discs. During collagen fibrillogenesis, lumican regulates the assembly of collagens into higher order fibrils, limiting the growth of fibrils in diameter. Lumican is present in the extracellular matrix of human articular cartilage at all ages, with a far greater abundance in the adult. The gene encoding human lumican maps to chromosome 12q21.3-q22.

Alternative Name:
KSPG lumican, LUM, LDC, SLRR2D, Keratan sulfate proteoglycan lumican, KSPG lumican, LDC, LUM, LUM, Lumican, Lumican precursor, SLRR2D,

Application Dilution:
WB:1:500-1:2,000
ICC:1:50-1:200
IHC:1:50-1:200
FC:1:50-1:100

Specificity: Lumican polyclonal antibody detects endogenous levels of Lumican protein.

Immunogen:
Recombinant protein within human Lumican aa 50-250.

MW: 38 kDa

Swiss-Prot: P51884(Human)

Purification & Purity:
ProA affinity purified

Format:
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Storage:
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.

For research use only, not for use in diagnostic procedure.