LXR alpha Polyclonal Antibody

Background:
NR1H3, also known as LXRA, is a liver X receptors, which form a subfamily of the nuclear receptor superfamily and are key regulators of macrophage function, controlling transcriptional programs involved in lipid homeostasis and inflammation.. It's also a ligand-activated LXRs and forms heterodimers with retinoid X receptor, then participates in regulating expression of target genes containing LXR response elements.

Research Area: Cancer, Cardiovascular, Epigenetics and Nuclear Signaling, Metabolism, Signal Transduction

Synonyms:
Liver X receptor alpha, LXR a, LXRA, NR1H3, NR1H3, Nuclear receptor subfamily 1 group H member 3, Oxysterols receptor LXR alpha, Oxysterols receptor LXR-alpha, RLD 1, RLD1

Immunogen: KLH conjugated Synthetic peptide corresponding to Mouse LXRα

Swissprot: Q9Z0Y9,Q62685

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 1% BSA and 50% glycerol, pH7.4

Concentration: 0.53 mg/mL
Dilution: IHC 1:400-1:1500

Storage:
Store at -20°C. Avoid freeze / thaw cycles.