LXRα Polyclonal Antibody
€0.00
In stock
SKU
ELK-ES3873
Catalog Number: ELK-ES3873
Reactivity: Human, Mouse, Rat
Applications: WB, IHC-p, ELISA
Information
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Reactivity: Human, Mouse, Rat
Applications: WB, IHC-p, ELISA
Information
Request Manual ELK-
Questions? Contact us!
Background:
nuclear receptor subfamily 1 group H member 3(NR1H3) Homo sapiens The protein encoded by this gene belongs to the NR1 subfamily of the nuclear receptor superfamily. The NR1 family members are key regulators of macrophage function, controlling transcriptional programs involved in lipid homeostasis and inflammation. This protein is highly expressed in visceral organs, including liver, kidney and intestine. It forms a heterodimer with retinoid X receptor (RXR), and regulates expression of target genes containing retinoid response elements. Studies in mice lacking this gene suggest that it may play an important role in the regulation of cholesterol homeostasis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011],
Alternative Names:
NR1H3, LXRA, Oxysterols receptor LXR-alpha, Liver X receptor alpha, Nuclear receptor subfamily 1 group H member 3
Immunogen: The antiserum was produced against synthesized peptide derived from the Internal region of human NR1H3. AA range:151-200
Isotype: Rabbit
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/ml
Observed band: 50
GeneID: NR1H3
Storage: -20°C/1 year
NOTE: For Research Use Only
nuclear receptor subfamily 1 group H member 3(NR1H3) Homo sapiens The protein encoded by this gene belongs to the NR1 subfamily of the nuclear receptor superfamily. The NR1 family members are key regulators of macrophage function, controlling transcriptional programs involved in lipid homeostasis and inflammation. This protein is highly expressed in visceral organs, including liver, kidney and intestine. It forms a heterodimer with retinoid X receptor (RXR), and regulates expression of target genes containing retinoid response elements. Studies in mice lacking this gene suggest that it may play an important role in the regulation of cholesterol homeostasis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011],
Alternative Names:
NR1H3, LXRA, Oxysterols receptor LXR-alpha, Liver X receptor alpha, Nuclear receptor subfamily 1 group H member 3
Immunogen: The antiserum was produced against synthesized peptide derived from the Internal region of human NR1H3. AA range:151-200
Isotype: Rabbit
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/ml
Observed band: 50
GeneID: NR1H3
Storage: -20°C/1 year
NOTE: For Research Use Only
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