Lyl-1 rabbit polyclonal, anti-human, mouse, rat

Backgroud: This gene represents a basic helix-loop-helix transcription factor. The encoded protein may play roles in blood vessel maturation and hematopoeisis. A translocation between this locus and the T cell receptor beta locus (GeneID 6957) on chromosome 7 has been associated with acute lymphoblastic leukemia. [provided by RefSeq, Sep 2010],disease:A chromosomal aberration involving LYL1 may be a cause of a form of T-cell acute lymphoblastic leukemia (T-ALL). Translocation t(7;19)(q35;p13) with TCRB.,similarity:Contains 1 basic helix-loop-helix (bHLH) domain.,subunit:Efficient DNA binding requires dimerization with another bHLH protein.,

Synonyms: LYL1, BHLHA18, Protein lyl-1, Class A basic helix-loop-helix protein 18, bHLHa18, Lymphoblastic leukemia-derived sequence 1

Gene Name: LYL1

Gene ID: 4066

SwissProt ID: P12980

Purification: Affinity purification

Storage: Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.