Lymphotoxin-alpha, LTα/ TNFβ (clone M42-5), anti-human, rat
€0.00
In stock
SKU
BMA1030
Catalog Number: BMA1030
Size: 100 μg
Isotype: Mouse IgG1
Reactivity: human, rat
Application(s): WB, ELISA
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Size: 100 μg
Isotype: Mouse IgG1
Reactivity: human, rat
Application(s): WB, ELISA
Request Information
Background:
Lymphotoxin-alpha, a member of theHYPERLINK "http://en.wikipedia.org/wiki/Tumor_necrosis_factors" \o "Tumor necrosis factors"tumor necrosis factor family, is a cytokine produced byHYPERLINK "http://en.wikipedia.org/wiki/Lymphocyte" \o "Lymphocyte"lymphocytes.It is a glycoprotein with a relative molecular mass (Mr) of 60,000-70,000.[1]LTA is highly inducible, secreted, and exists as homotrimeric molecule. It forms heterotrimers withHYPERLINK "http://en.wikipedia.org/wiki/LTB" \o "LTB"lymphotoxin-betawhich anchors lymphotoxin-alpha to the cell surface.LTA mediates a large variety of inflammatory, immunostimulatory, and antiviral responses. It is also involved in the formation of secondary lymphoid organs during development and plays a role in apoptosis.[2]
Immunogen:
A synthetic peptide (conjugated with KLH) corresponding to the region of humanLT-alpha.
Recommended Application:
Western Blot, WB(1:100-200); ELISA(1:5, 000)
Product Form: Liquid
Purification: Protein A purified
Storage Buffer: 1*PBS (pH7.4), 0.2% BSA, 40% Glycerol and 0.05% Sodium Azide.
Storage Instruction:
Store at 4℃ after thawing (1 week). Aliquot and store at -20℃ for long term (at least one year). Avoid repeated freeze and thaw cycles.
Lymphotoxin-alpha, a member of theHYPERLINK "http://en.wikipedia.org/wiki/Tumor_necrosis_factors" \o "Tumor necrosis factors"tumor necrosis factor family, is a cytokine produced byHYPERLINK "http://en.wikipedia.org/wiki/Lymphocyte" \o "Lymphocyte"lymphocytes.It is a glycoprotein with a relative molecular mass (Mr) of 60,000-70,000.[1]LTA is highly inducible, secreted, and exists as homotrimeric molecule. It forms heterotrimers withHYPERLINK "http://en.wikipedia.org/wiki/LTB" \o "LTB"lymphotoxin-betawhich anchors lymphotoxin-alpha to the cell surface.LTA mediates a large variety of inflammatory, immunostimulatory, and antiviral responses. It is also involved in the formation of secondary lymphoid organs during development and plays a role in apoptosis.[2]
Immunogen:
A synthetic peptide (conjugated with KLH) corresponding to the region of humanLT-alpha.
Recommended Application:
Western Blot, WB(1:100-200); ELISA(1:5, 000)
Product Form: Liquid
Purification: Protein A purified
Storage Buffer: 1*PBS (pH7.4), 0.2% BSA, 40% Glycerol and 0.05% Sodium Azide.
Storage Instruction:
Store at 4℃ after thawing (1 week). Aliquot and store at -20℃ for long term (at least one year). Avoid repeated freeze and thaw cycles.
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