LYRIC polyclonal, anti-human

Background:
Downregulates SLC1A2/EAAT2 promoter activity when expressed ectopically. Activates the nuclear factor kappa-B (NF-kappa-B) transcription factor. Promotes anchorage-independent growth of immortalized melanocytes and astrocytes which is a key component in tumor cell expansion. Promotes lung metastasis and also has an effect on bone and brain metastasis, possibly by enhancing the seeding of tumor cells to the target organ endothelium. Induces chemoresistance.

Synonyms: MTDH, 3D3, AEG-1, AEG1, LYRIC/3D3, metadherin

Cellular Location: Extracellular matrix Secreted

Immunogen:
A synthetic peptide of human LYRIC

Gene Symbol: LYRIC

Gene ID: 92140

Swiss prot: Q86UE4

Calculated MW: 64kDa

Recommended dilution:
IHC 1:25-100

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.