LYRM1 Polyclonal Antibody

Background:
The protein encoded by this gene belongs to the mitochondrial leucine/tyrosine/arginine motif family of proteins. Proteins of this family are short polypeptides that contain a leucine/tyrosine/arginine motif near the N-terminus. This gene is widely expressed with high levels in omental adipose tissue of obese individuals. In adipose tissue, the protein is localized to the nucleus where it promotes preadipocyte proliferation and lowers the rate of apoptosis to regulate adipose tissue homeostasis. Overexpression of this gene in adipocytes causes abnormal mitochondrial morphology and mitochondrial dysfunction. Alternative splicing results in multiple transcript variants.

Synonyms:
1110065L10Rik, 2310004B22Rik, 4930404J24Rik, A211C6.1, LYR motif containing 1, LYR motif containing protein 1, LYR motif-containing protein 1, LYRM 1, lyrm1, LYRM1, OTTHUMP00000162292, OTTMUSP00000031126, OTTMUSP00000031127, OTTMUSP00000031128, OTTMUSP00000031129, RGD1563498

Immunogen: Fusion protein of human LYRM1

Swissprot: O43325
Gene Accession: BC017039

Calculated MW: 14 kDa
Observed MW: Refer to figures

Purification Method: Antigen affinity purification

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Concentration: 0.84 mg/mL
Dilution: WB 1:500-1:2000, IHC 1:50-1:300, ELISA 1:5000-1:10000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.