LZTFL1 Polyclonal Antibody

Background:
This gene encodes a ubiquitously expressed protein that localizes to the cytoplasm. This protein interacts with Bardet-Biedl Syndrome (BBS) proteins and, through its interaction with BBS protein complexes, regulates protein trafficking to the ciliary membrane. Nonsense mutations in this gene cause a form of Bardet-Biedl Syndrome; a ciliopathy characterized in part by polydactyly, obesity, cognitive impairment, hypogonadism, and kidney failure. This gene may also function as a tumor suppressor; possibly by interacting with E-cadherin and the actin cytoskeleton and thereby regulating the transition of epithelial cells to mesenchymal cells. Alternative splicing of this gene results in multiple transcript variants.

Research Area: Epigenetics and Nuclear Signaling

Synonyms:
5530402H04Rik, 6130400H19Rik, AI414725, AW048545, BBS17, DKFZp686H2076, FLJ36386, Leucine zipper transcription factor like 1, Leucine zipper transcription factor like protein 1, Leucine zipper transcription factor-like protein 1, LZTFL 1, Lztfl1, Lztfl1 leucine zipper transcription factor-like 1, LZTL1, MGC106871, MGC108960, Putative uncharacterized protein DKFZp686H2076

Immunogen: Recombinant protein of human LZTFL1

Swissprot: Q9NQ48
Gene Accession: BC025988

Calculated MW: 35 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.3 mg/mL
Dilution: WB 1:500-1:2000, IHC 1:25-1:100

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-292641