LZTR1 polyclonal, anti-human, mouse, rat
€305.00
In stock
SKU
BS60279
Background:
LZTR1, leucine-zipper-like transcriptional regulator 1, is a member of the BTBkelch superfamily. LZTR1 contains 2 BTB (POZ) domains and 6 Kelch repeats. The BTB (broad-Complex, Tramtrack and Bric a brac) domain, also known as the POZ (POxvirus and Zinc finger) domain, is an N-terminal homodimerization domain that contains multiple copies of kelch repeats and/or C2 H2-type zinc fingers. Proteins that contain BTB domains are thought to be involved in transcriptional regulation via control of chromatin structure and function. LZTR1 is believed to function as a transcriptional regulator during embryogenesis. LZTR1 is expressed in fetal brain, heart, kidney, liver and lung and is found exclusively on the cytoplasmic surface of the Golgi network. LZTR1 likely contributes to the etiology of velocardiofacial/DiGeorge syndrome, as the LZTR1 gene lies within a chromosomal deletion region associated with the disease.
Alternative Name:
Leucine-zipper-like transcriptional regulator 1, LZTR-1, TCFL2
Application Dilution: WB: 1:500~1:1000
Specificity: LZTR1 polyclonal antibody detects endogenous levels of LZTR1 protein.
Immunogen:
A synthetic peptide corresponding to residues in Human LZTR1.
MW: ~ 95 kDa
Swis Prot.: Q8N653
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
LZTR1, leucine-zipper-like transcriptional regulator 1, is a member of the BTBkelch superfamily. LZTR1 contains 2 BTB (POZ) domains and 6 Kelch repeats. The BTB (broad-Complex, Tramtrack and Bric a brac) domain, also known as the POZ (POxvirus and Zinc finger) domain, is an N-terminal homodimerization domain that contains multiple copies of kelch repeats and/or C2 H2-type zinc fingers. Proteins that contain BTB domains are thought to be involved in transcriptional regulation via control of chromatin structure and function. LZTR1 is believed to function as a transcriptional regulator during embryogenesis. LZTR1 is expressed in fetal brain, heart, kidney, liver and lung and is found exclusively on the cytoplasmic surface of the Golgi network. LZTR1 likely contributes to the etiology of velocardiofacial/DiGeorge syndrome, as the LZTR1 gene lies within a chromosomal deletion region associated with the disease.
Alternative Name:
Leucine-zipper-like transcriptional regulator 1, LZTR-1, TCFL2
Application Dilution: WB: 1:500~1:1000
Specificity: LZTR1 polyclonal antibody detects endogenous levels of LZTR1 protein.
Immunogen:
A synthetic peptide corresponding to residues in Human LZTR1.
MW: ~ 95 kDa
Swis Prot.: Q8N653
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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