MACF1 antibody (clone 6G7), anti-human
€435.00
In stock
SKU
AC-AT2757a
Catalog Number: AC-AT2757a
Size: 100 µg
Isotype: mouse IgG1 Kappa
Applications: E
Request Information AC-AT2757a">Request Information
Size: 100 µg
Isotype: mouse IgG1 Kappa
Applications: E
Request Information AC-AT2757a">Request Information
Background:
The protein encoded by this gene belongs to the plakin family of cytoskeletal linker proteins. This protein family forms bridges between different cytoskeletal elements through specialized modular domains. The encoded protein is one of the largest size proteins identified in human cytoskeletal proteins. It has functional actin and microtubule binding domains, and it appears to stabilize actin at sites where microtubules and microfilaments meet. It may function in microtubule dynamics to facilitate actin-microtubule interactions at the cell periphery and to couple the microtubule network to cellular junctions. Alternatively spliced transcript variants encoding distinct isoforms have been described.
Other Names:
Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5, 620 kDa actin-binding protein, ABP620, Actin cross-linking family protein 7, Macrophin-1, Trabeculin-alpha, MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Antigen Type:
Recombinant Protein
Gene Name: MACF1 (HGNC:13664)
Gene ID: 23499
NCBI Accession: NP_036222.3
Primary Accession: Q9UPN3
Other Accession: BC007330
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
The protein encoded by this gene belongs to the plakin family of cytoskeletal linker proteins. This protein family forms bridges between different cytoskeletal elements through specialized modular domains. The encoded protein is one of the largest size proteins identified in human cytoskeletal proteins. It has functional actin and microtubule binding domains, and it appears to stabilize actin at sites where microtubules and microfilaments meet. It may function in microtubule dynamics to facilitate actin-microtubule interactions at the cell periphery and to couple the microtubule network to cellular junctions. Alternatively spliced transcript variants encoding distinct isoforms have been described.
Other Names:
Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5, 620 kDa actin-binding protein, ABP620, Actin cross-linking family protein 7, Macrophin-1, Trabeculin-alpha, MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Antigen Type:
Recombinant Protein
Gene Name: MACF1 (HGNC:13664)
Gene ID: 23499
NCBI Accession: NP_036222.3
Primary Accession: Q9UPN3
Other Accession: BC007330
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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