mAChR M2 polyclonal, anti-human, mouse
€388.00
In stock
SKU
BS6566
Background:
The muscarinic acetylcholine receptors (mAChR) mediate a variety of cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels. The mAChRs transducer signals by coupling to G-proteins, which then modulate several downstream effector proteins and ion channels. Five mAChR subtypes have been identified, designated M1 to M5. The five receptor subtypes show distinct patterns of tissue distribution, as well as distinct pharmacological and functional properties.
Alternative Name:
CHRM2, Muscarinic acetylcholine receptor M2
Application Dilution: WB: 1:500 - 1:2000, IF: 1:50 - 1:200
Specificity: mAChR M2 polyclonal antibody detects endogenous levels of mAChR M2 protein.
Immunogen:
Recombinant full length Human mAChR M2.
MW: ~ 52 kDa
Swis Prot.: P08172
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
The muscarinic acetylcholine receptors (mAChR) mediate a variety of cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels. The mAChRs transducer signals by coupling to G-proteins, which then modulate several downstream effector proteins and ion channels. Five mAChR subtypes have been identified, designated M1 to M5. The five receptor subtypes show distinct patterns of tissue distribution, as well as distinct pharmacological and functional properties.
Alternative Name:
CHRM2, Muscarinic acetylcholine receptor M2
Application Dilution: WB: 1:500 - 1:2000, IF: 1:50 - 1:200
Specificity: mAChR M2 polyclonal antibody detects endogenous levels of mAChR M2 protein.
Immunogen:
Recombinant full length Human mAChR M2.
MW: ~ 52 kDa
Swis Prot.: P08172
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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