MAD1 polyclonal, anti-mouse, rat

Quantity: 100 µg

Background:
Mitotic spindle assembly checkpoint protein MAD1 is a protein that in humans is encoded by the MAD1L1 gene. It is mapped to 7p22.3. MAD1L1 is a component of the mitotic spindle-assembly checkpoint that prevents the onset of anaphase until all chromosome are properly aligned at the metaphase plate. MAD1L1 can function as a homodimer. It localizes to the centrosome during metaphase and to the spindle midzone and the midbody during anaphase and telophase. MAD1L1 may also play a role in cell cycle control and tumor suppression.

Description:
Rabbit IgG polyclonal antibody for Mitotic spindle assembly checkpoint protein MAD1 (MAD1L1) detection. Tested with WB, IHC-P in Human, Mouse, Rat

Synonyms:
hMAD1 antibody, HsMAD1 antibody, MAD1 antibody, MAD1 mitotic arrest deficient like 1 (yeast) antibody, MAD1-like protein 1 antibody, MAD1L1 antibody, MD1L1_HUMAN antibody, Mitotic arrest deficient 1 antibody, Mitotic arrest deficient 1-like protein 1 antibody, Mitotic checkpoint MAD1 protein homolog antibody, Mitotic spindle assembly checkpoint protein MAD1 antibody, PIG9 antibody, Tax binding protein 181 antibody, Tax-binding protein 181 antibody, TP53I9 antibody, Tumor protein p53 inducible protein 9 antibody, TXBP181 antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
E.coli-derived human MAD1 recombinant protein (Position: L362-A632). Human MAD1 shares 81% amino acid (aa) sequence identity with mouse MAD1.E.coli-derived human MAD1 recombinant protein (Position: L362-A632). Human MAD1 shares 81% amino acid (aa) sequence identity with mouse MAD1.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: mouse, rat

Applications: WB, IHC-P

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.