MAdCAM1 polyclonal, anti-human

Quantity: 100 µg

Background:
MADCAM1(Mucosal Vascular Addressin Cell Adhesion Molecule 1), also known as MACAM1, is a protein that in humans is encoded by the MADCAM1 gene. By PCR-based analysis of somatic cell hybrids, Leung et al.(1997) mapped the MACAM1 gene to chromosome 19. The protein encoded by this gene is an endothelil cell adhesion molecule that interacts preferentially with the leukocyte beta7 integrin LPAM-1(alpha4 / beta7), L-selectin, and VLA-4(alpha4/beta1) on myeloid cells to direct leukocytes into mucosal and inflamed tissues. It is a member of the immunoglobulin superfamily and is similar to ICAM-1 and VCAM-1.

Description:
Rabbit IgG polyclonal antibody for Mucosal addressin cell adhesion molecule 1 (MADCAM1) detection. Tested with WB, IHC-P, IHC-F in Human.

Synonyms:
Addressin mucosal antibody, hMAdCAM 1 antibody, hMAdCAM-1 antibody, MACAM1 antibody, MADCA_HUMAN antibody, MAdCAM 1 antibody, MAdCAM-1 antibody, Madcam1 antibody, Mucosal addressin cell adhesion molecule 1 antibody, Mucosal vascular addressin cell adhesion molecule 1 antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
A synthetic peptide corresponding to a sequence in the middle region of human MAdCAM1(173-190aa EEPQGDEDVLFRVTERWR).

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human

Applications: WB, IHC-P, IHC-F

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.