MAEA polyclonal (N-term), anti-human

MAEA polyclonal (N-term), anti-human

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In stock
SKU
AC-AP17927a
Catalog Number: AC-AP17927a
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB37712
Applications: WB
Datasheet

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Background:
This gene product mediates the attachment of erythroblasts to macrophages. This attachment promotes terminal maturation and enucleation of erythroblasts, presumably by suppressing apoptosis. This protein is an integral membrane protein with the N-terminus on the extracellular side and the C-terminus on the cytoplasmic side of the cell. Two immunologically related isoforms of erythroblast macrophage protein with apparent molecular weights of 33 kD and 36 kD were detected in macrophage membranes; this gene encodes the larger isoform. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene, but the biological validity of some variants has not been determined.

Other Names:
Macrophage erythroblast attacher, Cell proliferation-inducing gene 5 protein, Erythroblast macrophage protein, Human lung cancer oncogene 10 protein, HLC-10, MAEA, EMP

Target/Specificity:
This MAEA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 16-42 amino acids from the N-terminal region of human MAEA.

Antigen Region:
16-42

Antigen Type: Synthetic Peptide

Gene Name: MAEA
Gene ID: 10296
Primary Accession: Q7L5Y9
NCBI Accession: NP_001017405.1;NP_005873.2
Other Accession: Q6GR10; Q5RKJ1; Q4VC33; Q4R9A8; Q7SXR3; Q5F398; Q3MHJ2; NP_001017405.1; NP_005873.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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