MAEL Antibody (C-term) Blocking Peptide
€363.00
In stock
SKU
AC-BP8889b
Background:
MAEL plays a central role during spermatogenesis by repressing transposable elements and prevent their mobilization, which is essential for the germline integrity. It acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. Its association with piP-bodies suggests a participation in the secondary piRNAs metabolic process. Required for localization of germ-cell factors to the meiotic nuage (By similarity).
Other Names:
Protein maelstrom homolog, MAEL
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP8889b was selected from the C-term region of human MAEL. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: MAEL
Gene ID: 84944
Primary Accession: Q96JY0
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
MAEL plays a central role during spermatogenesis by repressing transposable elements and prevent their mobilization, which is essential for the germline integrity. It acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. Its association with piP-bodies suggests a participation in the secondary piRNAs metabolic process. Required for localization of germ-cell factors to the meiotic nuage (By similarity).
Other Names:
Protein maelstrom homolog, MAEL
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP8889b was selected from the C-term region of human MAEL. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: MAEL
Gene ID: 84944
Primary Accession: Q96JY0
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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