MAFB polyclonal, anti-human, mouse, rat
€388.00
In stock
SKU
BS71024
Background:
MafB is expressed in a wide variety of tissues and encodes a protein containing a typical bZip motif in its carboxy-terminal region. As a transcriptional activator, MafB plays a pivotal role in regulating lineage-specific gene expression during hematopoiesis by repressing Ets-1-mediated transcription of key erythroid-specific genes in myeloid cells. c-Maf interacts with the c-Myb DNA binding domain and forms Myb-Maf complexes, which inturn mediate the cooperative interactions between c-Myb and Ets-1 during early myeloid cell differentiation.
Alternative Name:
Transcription factor MafB, Maf-B, V-maf musculoaponeurotic fibrosarcoma oncogene homolog B, MAFB, KRML
Application Dilution: WB: 1:500 - 1:2000
Specificity: MAFB polyclonal antibody detects endogenous levels of MAFB protein.
Immunogen:
Recombinant protein of human MAFB.
MW: ~ 36 kDa
Swis Prot.: Q9Y5Q3
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
MafB is expressed in a wide variety of tissues and encodes a protein containing a typical bZip motif in its carboxy-terminal region. As a transcriptional activator, MafB plays a pivotal role in regulating lineage-specific gene expression during hematopoiesis by repressing Ets-1-mediated transcription of key erythroid-specific genes in myeloid cells. c-Maf interacts with the c-Myb DNA binding domain and forms Myb-Maf complexes, which inturn mediate the cooperative interactions between c-Myb and Ets-1 during early myeloid cell differentiation.
Alternative Name:
Transcription factor MafB, Maf-B, V-maf musculoaponeurotic fibrosarcoma oncogene homolog B, MAFB, KRML
Application Dilution: WB: 1:500 - 1:2000
Specificity: MAFB polyclonal antibody detects endogenous levels of MAFB protein.
Immunogen:
Recombinant protein of human MAFB.
MW: ~ 36 kDa
Swis Prot.: Q9Y5Q3
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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