MAG (C-term) polyclonal, anti-human, mouse, rat

Protein Family: Cell Adhesion Molecules, CAM Ligands, Glycan Binding Proteins

Pathway and Disease: Signaling Molecules and Interaction

Description:
Myelin-associated glycoprotein (MAG) is an adhesion molecule in postnatal neural development that mediates sialic acid dependent cell-cell interactions between neuronal and myelinating cells. MAG preferentially binds to alpha-2,3-linked sialic acid. Isoform L-MAG is critical for the formation of myelin in the CNS, whereas isoform S-MAG is sufficient to maintain the integrity of myelin in PNS. MAG belongs to the immunoglobulin superfamily SIGLEC, sialic acid binding lg-like lectin.

Alternate Names: Myelin-associated glycoprotein, Siglec-4a, MAG, GMA

Application Notes: E: 1:500-1:1,000; WB: 1:200-1:500; IHC: 1:200-1:500

Accession No.: P20916

Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human MAG.

Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 25% glycerol, 1 mg/ml BSA with 0.09% sodium azide. Antibody was purified by Protein-A affinity chromatography.

Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.