MAGEA10 polyclonal (C-term), anti-human
€0.00
In stock
SKU
AC-AP6160a
Catalog Number: AC-AP6160a
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB2244
Applications: IHC-P, WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB2244
Applications: IHC-P, WB
Datasheet
Request Information
Background:
MAGEA10 is a member of the MAGEA gene family. The members of this family have their entire coding sequences located in the last exon, and the encoded proteins show 50 to 80% sequence identity between each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are expressed at a high level in a number of tumors of various histologic types, and are silent in normal tissues with the exception of testis and placenta. The MAGEA genes are clustered on chromosome Xq28. They may be implicated in some hereditary disorders, such as dyskeratosis congenita.
Other Names:
Melanoma-associated antigen 10, Cancer/testis antigen 110, CT110, MAGE-10 antigen, MAGEA10, MAGE10
Target/Specificity:
This MAGEA10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 324-353 amino acids from the C-terminal region of human MAGEA10.
Antigen Region:
324-353
Antigen Type: Synthetic Peptide
Gene Name: MAGEA10
Gene ID: 4109
Primary Accession: P43363
NCBI Accession: NP_001011543.2;NP_001238757.1;NP_066386.2
Other Accession: NP_066386
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
MAGEA10 is a member of the MAGEA gene family. The members of this family have their entire coding sequences located in the last exon, and the encoded proteins show 50 to 80% sequence identity between each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are expressed at a high level in a number of tumors of various histologic types, and are silent in normal tissues with the exception of testis and placenta. The MAGEA genes are clustered on chromosome Xq28. They may be implicated in some hereditary disorders, such as dyskeratosis congenita.
Other Names:
Melanoma-associated antigen 10, Cancer/testis antigen 110, CT110, MAGE-10 antigen, MAGEA10, MAGE10
Target/Specificity:
This MAGEA10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 324-353 amino acids from the C-terminal region of human MAGEA10.
Antigen Region:
324-353
Antigen Type: Synthetic Peptide
Gene Name: MAGEA10
Gene ID: 4109
Primary Accession: P43363
NCBI Accession: NP_001011543.2;NP_001238757.1;NP_066386.2
Other Accession: NP_066386
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
| Is Featured? | No |
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