MAGEA2 polyclonal (N-term), anti-human
€0.00
In stock
SKU
AC-AP6164a
Catalog Number: AC-AP6164a
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB2194
Applications: WB, FC
Datasheet
Request Information
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB2194
Applications: WB, FC
Datasheet
Request Information
Background:
MAGEA2 is a member of the MAGEA gene family. The members of this family have their entire coding sequences located in the last exon, and the encoded proteins show 50 to 80% sequence identity between each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are expressed at a high level in a number of tumors of various histologic types, and are silent in normal tissues with the exception of testis and placenta. The MAGEA genes are clustered on chromosome Xq28. They may be implicated in some hereditary disorders, such as dyskeratosis congenita. This gene has two identical copies at different loci.
Other Names:
Melanoma-associated antigen 2, Cancer/testis antigen 12, CT12, MAGE-2 antigen, MAGEA2, MAGE2, MAGEA2A
Target/Specificity:
This MAGEA2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 81-108 amino acids from the N-terminal region of human MAGEA2.
Antigen Region:
81-108
Antigen Type: Synthetic Peptide
Gene Name: MAGEA2
Gene ID: 266740;4101
Primary Accession: P43356
NCBI Accession: NP_005352.1;NP_705692.1;NP_786884.1;NP_786885.1
Other Accession: NP_005352
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
MAGEA2 is a member of the MAGEA gene family. The members of this family have their entire coding sequences located in the last exon, and the encoded proteins show 50 to 80% sequence identity between each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are expressed at a high level in a number of tumors of various histologic types, and are silent in normal tissues with the exception of testis and placenta. The MAGEA genes are clustered on chromosome Xq28. They may be implicated in some hereditary disorders, such as dyskeratosis congenita. This gene has two identical copies at different loci.
Other Names:
Melanoma-associated antigen 2, Cancer/testis antigen 12, CT12, MAGE-2 antigen, MAGEA2, MAGE2, MAGEA2A
Target/Specificity:
This MAGEA2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 81-108 amino acids from the N-terminal region of human MAGEA2.
Antigen Region:
81-108
Antigen Type: Synthetic Peptide
Gene Name: MAGEA2
Gene ID: 266740;4101
Primary Accession: P43356
NCBI Accession: NP_005352.1;NP_705692.1;NP_786884.1;NP_786885.1
Other Accession: NP_005352
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
|---|
Write Your Own Review