MAGEA9 polyclonal, anti-human, mouse, rat
€305.00
In stock
SKU
BS61025
Background:
The melanoma-associated antigen (MAGE) family consists of a number of antigens recognized by cytotoxic T lymphocytes. The MAGE genes were initially isolated from different kinds of tumors and, based on their virtually exclusive tumor-specific expression in adult tissues, they have been used as targets for cancer immunotherapy. MAGE genes encode for tumor-rejection antigens and are expressed in tumors of different histologic types as well as in normal testis and placenta. MAGE-A9 (melanoma-associated antigen 9), also known as MAGE9 or CT1.9 (cancer/testis antigen 1.9), is a 315 amino acid protein that contains one MAGE domain. Like most MAGE family members, MAGE-A9 is expressed in several types of tumors, including lung cancer, breast cancer and melanoma, and is thought to play an important role in tumor progression and transformation. Additionally, MAGE-A9 may be involved in embryonic development.
Alternative Name:
Melanoma-associated antigen 9, Cancer/testis antigen 1.9, CT1.9, MAGE-9 antigen, MAGEA9, MAGE9, MAGEA9A, MAGEA9B
Application Dilution: WB: 1:500~1:1000
Specificity: MAGEA9 polyclonal antibody detects endogenous levels of MAGEA9 protein.
Immunogen:
A synthetic peptide corresponding to residues in Human MAGEA9.
MW: ~ 35 kDa
Swis Prot.: P43362
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
The melanoma-associated antigen (MAGE) family consists of a number of antigens recognized by cytotoxic T lymphocytes. The MAGE genes were initially isolated from different kinds of tumors and, based on their virtually exclusive tumor-specific expression in adult tissues, they have been used as targets for cancer immunotherapy. MAGE genes encode for tumor-rejection antigens and are expressed in tumors of different histologic types as well as in normal testis and placenta. MAGE-A9 (melanoma-associated antigen 9), also known as MAGE9 or CT1.9 (cancer/testis antigen 1.9), is a 315 amino acid protein that contains one MAGE domain. Like most MAGE family members, MAGE-A9 is expressed in several types of tumors, including lung cancer, breast cancer and melanoma, and is thought to play an important role in tumor progression and transformation. Additionally, MAGE-A9 may be involved in embryonic development.
Alternative Name:
Melanoma-associated antigen 9, Cancer/testis antigen 1.9, CT1.9, MAGE-9 antigen, MAGEA9, MAGE9, MAGEA9A, MAGEA9B
Application Dilution: WB: 1:500~1:1000
Specificity: MAGEA9 polyclonal antibody detects endogenous levels of MAGEA9 protein.
Immunogen:
A synthetic peptide corresponding to residues in Human MAGEA9.
MW: ~ 35 kDa
Swis Prot.: P43362
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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