MAGEB18 Polyclonal Antibody

Background:
The melanoma-associated antigen (MAGE) family consists of a number of antigens recognized by cytotoxic T lymphocytes. The MAGE genes were initially isolated from different kinds of tumors and, based on their virtually exclusive tumor-specific expression in adult tissues, they have been used as targets for cancer immunotherapy. MAGE genes encode for tumor-rejection antigens that are expressed in tumors of different histologic types and in normal testis and placenta. MAGE-B18 (melanoma-associated antigen B18) is a 343 amino acid protein that contains one MAGE domain and may be involved in tumorigenesis. The gene encoding MAGE-B18 maps to human chromosome X, which contains nearly 153 million base pairs and houses over 1, 000 genes.

Research Area: Cancer, Immunology

Synonyms:
B430216B18Rik, MAGBI, MAGE-B18 antigen, MAGEB18, MAGEB18 antigen, Melanoma antigen family B, 18, Melanoma-associated antigen B18, MGC114496, RGD1560369, RP23-289C5.3

Immunogen: Synthetic peptide of human MAGEB18

Swissprot: Q96M61
Gene Accession: NP_775970

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.7 mg/mL
Dilution: IHC 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-131175/sc-131177/sc-131178