MAGEB2 Antibody (N-term) Blocking Peptide
€363.00
In stock
SKU
AC-BP6172a
Background:
MAGEB2 is a member of the MAGEB gene family. The members of this family have their entire coding sequences located in the last exon, and the encoded proteins show 50 to 68% sequence identity to each other. The promoters and first exons of the MAGEB genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. This gene is localized in the DSS (dosage-sensitive sex reversal) critical region. It is expressed in testis and placenta, and in a significant fraction of tumors of various histological types. The MAGEB genes are clustered on chromosome Xp22-p21.
Other Names:
Melanoma-associated antigen B2, Cancer/testis antigen 32, CT32, DSS-AHC critical interval MAGE superfamily 6, DAM6, MAGE XP-2 antigen, MAGE-B2 antigen, MAGEB2
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP6172a was selected from the N-term region of human MAGEB2 . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: MAGEB2
Gene ID: 4113
Primary Accession: O15479
Other Accession: NP_002355
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
MAGEB2 is a member of the MAGEB gene family. The members of this family have their entire coding sequences located in the last exon, and the encoded proteins show 50 to 68% sequence identity to each other. The promoters and first exons of the MAGEB genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. This gene is localized in the DSS (dosage-sensitive sex reversal) critical region. It is expressed in testis and placenta, and in a significant fraction of tumors of various histological types. The MAGEB genes are clustered on chromosome Xp22-p21.
Other Names:
Melanoma-associated antigen B2, Cancer/testis antigen 32, CT32, DSS-AHC critical interval MAGE superfamily 6, DAM6, MAGE XP-2 antigen, MAGE-B2 antigen, MAGEB2
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP6172a was selected from the N-term region of human MAGEB2 . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: MAGEB2
Gene ID: 4113
Primary Accession: O15479
Other Accession: NP_002355
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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