MAGEB2 polyclonal (N-term), anti-human

MAGEB2 polyclonal (N-term), anti-human

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In stock
SKU
AC-AP6172a
Catalog Number: AC-AP6172a
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB2245-2246
Applications: WB, IHC-P
Datasheet

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Background:
MAGEB2 is a member of the MAGEB gene family. The members of this family have their entire coding sequences located in the last exon, and the encoded proteins show 50 to 68% sequence identity to each other. The promoters and first exons of the MAGEB genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. This gene is localized in the DSS (dosage-sensitive sex reversal) critical region. It is expressed in testis and placenta, and in a significant fraction of tumors of various histological types. The MAGEB genes are clustered on chromosome Xp22-p21.

Other Names:
Melanoma-associated antigen B2, Cancer/testis antigen 32, CT32, DSS-AHC critical interval MAGE superfamily 6, DAM6, MAGE XP-2 antigen, MAGE-B2 antigen, MAGEB2

Target/Specificity:
This MAGEB2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 4-33 amino acids from the N-terminal region of human MAGEB2.

Antigen Region:
4-33

Antigen Type: Synthetic Peptide

Gene Name: MAGEB2
Gene ID: 4113
Primary Accession: O15479
NCBI Accession: NP_002355.2
Other Accession: NP_002355
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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