MAGEC1 Antibody (C-term) Blocking Peptide
€363.00
In stock
SKU
AC-BP6175a
Background:
MAGEC1 is a member of the melanoma antigen gene (MAGE) family. The proteins of this family are tumor-specific antigens that can be recognized by autologous cytolytic T lymphocytes. This protein contains a large number of unique short repetitive sequences in front of the MAGE-homologous sequence, thus is about 800 residues longer than the other MAGE proteins. This gene is expressed in a significant proportion of tumors of various histological types, whereas it is silent in normal tissues, except testis. The function of this gene is unknown.
Other Names:
Melanoma-associated antigen C1, Cancer/testis antigen 71, CT71, MAGE-C1 antigen, MAGEC1
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP6175a was selected from the C-term region of human MAGEC1 . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: MAGEC1
Gene ID: 9947
Primary Accession: O60732
Other Accession: NP_005453
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
MAGEC1 is a member of the melanoma antigen gene (MAGE) family. The proteins of this family are tumor-specific antigens that can be recognized by autologous cytolytic T lymphocytes. This protein contains a large number of unique short repetitive sequences in front of the MAGE-homologous sequence, thus is about 800 residues longer than the other MAGE proteins. This gene is expressed in a significant proportion of tumors of various histological types, whereas it is silent in normal tissues, except testis. The function of this gene is unknown.
Other Names:
Melanoma-associated antigen C1, Cancer/testis antigen 71, CT71, MAGE-C1 antigen, MAGEC1
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP6175a was selected from the C-term region of human MAGEC1 . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: MAGEC1
Gene ID: 9947
Primary Accession: O60732
Other Accession: NP_005453
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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