MAGEL2 polyclonal (C-term), anti-human
€0.00
In stock
SKU
AC-AP6181a
Catalog Number: AC-AP6181a
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB2131
Applications: WB, IHC-P
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB2131
Applications: WB, IHC-P
Datasheet
Request Information
Background:
Melanoma-associated antigen (MAGE) are completely silent in normal tissues, with the exception of male germ cells, and, for some of them, placenta. These antigens ought to be strictly tumor specific, expressed in tumor cells of various histological types. Because of their specific expression on tumor cells, these antigens are of particular interest for antitumor immunotherapy. Genes of the MAGE family direct the expression of tumor antigens that are recognized on a human melanoma by autologous cytolytic T lymphocytes. Though the function of MAGE is unknown, may play a role in embryonal development and tumor transformation or aspects of tumor progression.
Other Names:
MAGE-like protein 2, Necdin-like protein 1, Protein nM15, MAGEL2, NDNL1
Target/Specificity:
This MAGEL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 499-529 amino acids from the C-terminal region of human MAGEL2.
Antigen Region:
499-529
Antigen Type: Synthetic Peptide
Gene Name: MAGEL2
Gene ID: 54551
Primary Accession: Q9UJ55
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Melanoma-associated antigen (MAGE) are completely silent in normal tissues, with the exception of male germ cells, and, for some of them, placenta. These antigens ought to be strictly tumor specific, expressed in tumor cells of various histological types. Because of their specific expression on tumor cells, these antigens are of particular interest for antitumor immunotherapy. Genes of the MAGE family direct the expression of tumor antigens that are recognized on a human melanoma by autologous cytolytic T lymphocytes. Though the function of MAGE is unknown, may play a role in embryonal development and tumor transformation or aspects of tumor progression.
Other Names:
MAGE-like protein 2, Necdin-like protein 1, Protein nM15, MAGEL2, NDNL1
Target/Specificity:
This MAGEL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 499-529 amino acids from the C-terminal region of human MAGEL2.
Antigen Region:
499-529
Antigen Type: Synthetic Peptide
Gene Name: MAGEL2
Gene ID: 54551
Primary Accession: Q9UJ55
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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