MAGI3 polyclonal (C-Term), anti-human
€0.00
In stock
SKU
AC-AP21866b
Catalog Number: AC-AP21866b
Size: 50 µl, 200 µl
Isotype: Rabbit IgG
Clone Name: RB53923
Applications: WB
Datasheet
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Size: 50 µl, 200 µl
Isotype: Rabbit IgG
Clone Name: RB53923
Applications: WB
Datasheet
Request Information
Background:
Acts as a scaffolding protein at cell-cell junctions, thereby regulating various cellular and signaling processes. Cooperates with PTEN to modulate the kinase activity of AKT1. Its interaction with PTPRB and tyrosine phosphorylated proteins suggests that it may link receptor tyrosine phosphatase with its substrates at the plasma membrane. In polarized epithelial cells, involved in efficient trafficking of TGFA to the cell surface. Regulates the ability of LPAR2 to activate ERK and RhoA pathways. Regulates the JNK signaling cascade via its interaction with FZD4 and VANGL2.
Other Names:
Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3, Membrane-associated guanylate kinase inverted 3, MAGI-3, MAGI3, KIAA1634
Target/Specificity:
This MAGI3 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 1330-1360 amino acids from human MAGI3.
Gene Name: MAGI3
Gene ID: 260425
Primary Accession: Q5TCQ9
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Acts as a scaffolding protein at cell-cell junctions, thereby regulating various cellular and signaling processes. Cooperates with PTEN to modulate the kinase activity of AKT1. Its interaction with PTPRB and tyrosine phosphorylated proteins suggests that it may link receptor tyrosine phosphatase with its substrates at the plasma membrane. In polarized epithelial cells, involved in efficient trafficking of TGFA to the cell surface. Regulates the ability of LPAR2 to activate ERK and RhoA pathways. Regulates the JNK signaling cascade via its interaction with FZD4 and VANGL2.
Other Names:
Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3, Membrane-associated guanylate kinase inverted 3, MAGI-3, MAGI3, KIAA1634
Target/Specificity:
This MAGI3 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 1330-1360 amino acids from human MAGI3.
Gene Name: MAGI3
Gene ID: 260425
Primary Accession: Q5TCQ9
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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