Malic enzyme 1 rabbit polyclonal, anti-human, mouse, rat

Backgroud: This gene encodes a cytosolic, NADP-dependent enzyme that generates NADPH for fatty acid biosynthesis. The activity of this enzyme, the reversible oxidative decarboxylation of malate, links the glycolytic and citric acid cycles. The regulation of expression for this gene is complex. Increased expression can result from elevated levels of thyroid hormones or by higher proportions of carbohydrates in the diet. [provided by RefSeq, Jul 2008],catalytic activity:(S)-malate + NADP(+) = pyruvate + CO(2) + NADPH.,cofactor:Divalent metal cations. Prefers magnesium or manganese.,online information:The Singapore human mutation and polymorphism database,similarity:Belongs to the malic enzymes family.,subunit:Homotetramer.,tissue specificity:Expressed in all tissues tested including liver, placenta and white adipose tissue.,

Synonyms: ME1, NADP-dependent malic enzyme, NADP-ME, Malic enzyme 1

Gene Name: ME1

Gene ID: 4199

SwissProt ID: P48163

Purification: Affinity purification

Storage: Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.