MAML1 / Mastermind polyclonal, anti-human

Background:
This protein is the human homolog of mastermind, a Drosophila protein that plays a role in the Notch signaling pathway involved in cell-fate determination. There is in vitro evidence that the human homolog forms a complex with the intracellular portion of human Notch receptors and can increase expression of a Notch-induced gene. This evidence supports its proposed function as a transcriptional co-activator in the Notch signaling pathway.

Other Names:
Mastermind-like protein 1, Mam-1, MAML1 (HGNC:13632)

Antigen Types:
Synthetic Peptide

Gene Name:
MAML1 (HGNC:13632)
Gene ID:
9794
Primary Accession: Q92585
Other Accession: NP_055572;9794;