MAN1B1 Polyclonal Antibody

Background:
mannosidase alpha class 1B member 1(MAN1B1) Homo sapiens This gene encodes an enzyme belonging to the glycosyl hydrolase 47 family. This enzyme functions in N-glycan biosynthesis, and is a class I alpha-1,2-mannosidase that specifically converts Man9GlcNAc to Man8GlcNAc isomer B. It is required for N-glycan trimming to Man5-6GlcNAc2 in the endoplasmic-reticulum-associated degradation pathway. Mutations in this gene cause autosomal-recessive intellectual disability. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 11. [provided by RefSeq, Dec 2011],

Alternative Names:
MAN1B1, Endoplasmic reticulum mannosyl-oligosaccharide 1, 2-alpha-mannosidase, ER alpha-1,2-mannosidase, ER mannosidase 1, ERMan1, Man9GlcNAc2-specific-processing alpha-mannosidase, Mannosidase alpha

Immunogen: Synthesized peptide derived from MAN1B1 . at AA range: 100-180

Isotype: Rabbit

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration: 1 mg/ml

Observed band: 80

GeneID: MAN1B1

Storage: -20°C/1 year

NOTE: For Research Use Only