MAP2K1 (phospho-T286) polyclonal, anti-human, mouse, rat

Background:
The protein encoded by this gene is a member of the dual specificity protein kinase family, which acts as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein kinase lies upstream of MAP kinases and stimulates the enzymatic activity of MAP kinases upon wide variety of extra- and intracellular signals. As an essential component of MAP kinase signal transduction pathway, this kinase is involved in many cellular processes such as proliferation, differentiation, transcription regulation and development.

Synonyms: CFC3, MAPKK1, MEK1, MKK1, PRKMK1

Cellular Location: Cytoplasm Membrane Nucleus Peripheral membrane protein centrosome cytoskeleton microtubule organizing center spindle pole body

Immunogen:
A phospho specific peptide corresponding to residues surrounding T286 of human MAP2K1

Gene Symbol: Phospho-MAP2K1-T286

Gene ID: 5604

Swiss prot: Q02750

Calculated MW: 43kDa

Recommended dilution:
WB 1:500-2000

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.