map2k3 (clone 8A11-G11-G11), anti-human, rat

Background:
This gene encodes a member of the dual specificity protein kinase family, which functions as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein phosphorylates and activates p38 MAP kinase in response to inflammatory cytokines or environmental stress. As an essential component of p38 MAP kinase mediated signal transduction pathway, this gene is involved in many cellular processes such as stress induced cell cycle arrest, transcription activation and apoptosis.

Synonyms: MAPKK6, MEK6, MKK6, PRKMK6, SAPKK-3, SAPKK3

Cellular Location: Cytoplasm Nucleus cytoskeleton

Immunogen:
Purified recombinant human MKK6 protein fragments expressed in E.coli.

Gene Symbol: map2k3

Gene ID: 5608

Swiss prot: P52564

Calculated MW: 40kDa

Recommended dilution:
WB 1:1000

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.